Predicting experimental success: a retrospective case-control study using the rat intraluminal thread model of stroke

• Main Authors: Lisa Liebenstund (Author), Mark Coburn (Author), Christina Fitzner (Author), Antje Willuweit (Author), Karl-Josef Langen (Author), Jingjin Liu (Author), Michael Veldeman (Author), Anke Höllig (Author)
• Format: Book
• Published: The Company of Biologists, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The poor translational success rate of preclinical stroke research may partly be due to inaccurate modelling of the disease. We provide data on transient middle cerebral artery occlusion (tMCAO) experiments, including detailed intraoperative monitoring to elaborate predictors indicating experimental...