Study of Linearization of Hill Dose-Effect Curve with Metabolic Velocity Instead of Drug Concentration

• 主要な著者: Run-Nan LIU (著者), Yu TANG (著者), Ping-An LIU (著者), Wen-Long LIU (著者), Qi-Meng FAN (著者), Si-Yang CHEN (著者), Peng HE (著者), Hai-Ying LI (著者), Fu-Yuan HE (著者), Kai-Wen DENG (著者)
• フォーマット: 図書
• 出版事項: KeAi Communications Co., Ltd., 2018-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

ABSTRACT: Objective To explore the velocity-effect relationship in order to the establish linearization of effect on an equation with regard to the consistency of the Hill dose-effect expression with the metabolic kinetics of receptors.Methods The linear velocity-effect expression was obtained by so...