Novel compound FLZ alleviates rotenone-induced PD mouse model by suppressing TLR4/MyD88/NF-κB pathway through microbiota-gut-brain axis

• Main Authors: Zhe Zhao (Author), Fangyuan Li (Author), Jingwen Ning (Author), Ran Peng (Author), Junmei Shang (Author), Hui Liu (Author), Meiyu Shang (Author), Xiu-Qi Bao (Author), Dan Zhang (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkinson's disease (PD) is the second most common neurodegenerative disease, but none of the current treatments for PD can halt the progress of the disease due to the limited understanding of the pathogenesis. In PD development, the communication between the brain and the gastrointestinal syst...