Profibrotic Inflammatory Cytokines and Growth Factors Are Predicted as the Key Targets of <i>Uncaria gambir</i> (Hunter) Roxb. in Keloids: An Epistatic and Molecular Simulation Approach

• Main Authors: Sri Suciati Ningsih (Author), Fadilah Fadilah (Author), Sri Widia A. Jusman (Author), Rahimi Syaidah (Author), Takashi Yashiro (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Keloid is characterized as the fibrotic tissue resulting from the increase of fibroblast activity. <i>Uncaria gambir</i> (Hunter) Roxb. possesses bioactive compounds that have potential as antifibrotic agents, while the mechanism of action in keloid has not yet been elucidated. The aim o...