Proteasome Inhibitors Protect Against Degeneration of Nigral Dopaminergic Neurons in Hemiparkinsonian Rats

• Main Authors: Masatoshi Inden (Author), Jun-ichi Kondo (Author), Yoshihisa Kitamura (Author), Kazuyuki Takata (Author), Kaneyasu Nishimura (Author), Takashi Taniguchi (Author), Hideyuki Sawada (Author), Shun Shimohama (Author)
• Format: Book
• Published: Elsevier, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkinson's disease is characterized by dopaminergic neuronal death and the presence of Lewy bodies in the substantia nigra pars compacta (SNpc). α-Synuclein and ubiquitin are components of Lewy bodies, but the process of Lewy body formation and the relationship between inclusion formation and...