Proteasome Inhibitors Protect Against Degeneration of Nigral Dopaminergic Neurons in Hemiparkinsonian Rats

• Päätekijät: Masatoshi Inden (Tekijä), Jun-ichi Kondo (Tekijä), Yoshihisa Kitamura (Tekijä), Kazuyuki Takata (Tekijä), Kaneyasu Nishimura (Tekijä), Takashi Taniguchi (Tekijä), Hideyuki Sawada (Tekijä), Shun Shimohama (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2005-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Parkinson's disease is characterized by dopaminergic neuronal death and the presence of Lewy bodies in the substantia nigra pars compacta (SNpc). α-Synuclein and ubiquitin are components of Lewy bodies, but the process of Lewy body formation and the relationship between inclusion formation and...