Synthesis, Physicochemical and Biological Study of Gallium-68- and Lutetium-177-Labeled VEGF-A₁₆₅/NRP-1 Complex Inhibitors Based on Peptide A7R and Branched Peptidomimetic

• Main Authors: Katarzyna Masłowska (Author), Ewa Witkowska (Author), Dagmara Tymecka (Author), Paweł Krzysztof Halik (Author), Aleksandra Misicka (Author), Ewa Gniazdowska (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuropilin-1 (NRP-1) is a surface receptor found on many types of cancer cells. The overexpression of NRP-1 and its interaction with vascular endothelial growth factor-165 (VEGF₁₆₅) are associated with tumor growth and metastasis. Therefore, compounds that block the VEGF<su...