MSCs Contribute to the Conversion of Ly6Chigh Monocytes into Ly6Clow Subsets under AMI

• Main Authors: Wenbin Lu (Author), Genshan Ma (Author), Zulong Sheng (Author), Qingjie Wang (Author), Lijuan Chen (Author), Junhua Qi (Author), Ronghui Shi (Author), Jingjing Ji (Author), Zhenjun Ji (Author), Qiming Dai (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Ly6Chigh monocytes are inflammatory cells that accumulate in an infarcted myocardium, and Ly6Clow monocytes are believed to be reparative and curb myocardial remodeling. NR4A1 is a novel target for modulating the inflammatory phenotype of monocytes during atherogenesis. Objectives. We ai...