Paracrine Fibroblast Growth Factor 1 Functions as Potent Therapeutic Agent for Intrahepatic Cholestasis by Downregulating Synthesis of Bile Acid

• 主要な著者: Huan Lin (著者), Chuanren Zhou (著者), Yushu Hou (著者), Qi Li (著者), Guanting Qiao (著者), Yang Wang (著者), Zhifeng Huang (著者), Jianlou Niu (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Endocrine fibroblast growth factor (FGF) 19 has been shown to be capable of maintaining bile acid (BA) homeostasis and thus hold promise to be a potential therapeutic agent for cholestasis liver disease. However, whether paracrine FGFs possess this BA regulatory activity remains to be determined. In...