In-depth LC-MS and in-vitro studies of a triterpenoid saponin capilliposide-A metabolism modulation in gut microbiota of mice

• Main Authors: Huan Zhao (Author), Xueli Hu (Author), Shenghong Guan (Author), Jinhong Cai (Author), Xiaohan Li (Author), Jiaxi Fang (Author), Bo Lin (Author), Wei Zhu (Author), Jingkui Tian (Author), Juan Jin (Author), Qiang He (Author), Xiaoyong Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Some herbal ingredients can reshape the composition of the gut microbiome as well as its metabolites. At the same time, the gut microbiota can also affect drug metabolism. A large number of studies have reported that saponins are biotransformed under the action of intestinal microorgan...