Thyroid Disorders in Patients Treated with Dimethyl Fumarate for Multiple Sclerosis: A Retrospective Observational Study

• Main Authors: Cédric O. Renaud (Author), Panos G. Ziros (Author), Amandine Mathias (Author), Caroline Pot (Author), Gerasimos P. Sykiotis (Author)
• 格式: 图书
• 出版: MDPI AG, 2022-05-01T00:00:00Z.
• 主题: article
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Background: Dimethyl fumarate (DMF), a drug used for the treatment of multiple sclerosis (MS) and psoriasis, has been shown to activate the Keap1/Nrf2 antioxidant response. Nrf2 exerts pleiotropic roles in the thyroid gland; among others, single nucleotide polymorphisms (SNPs) in the gene encoding N...