Hydralazine reduces myocardial tissue damage in rats submitted to chronic inhibition of systemic nitric oxide synthesis during 4, 14 and 28 days

• Main Authors: Ricardo Xavier-Vidal (Author), Kalil Madi (Author), Aline de Abreu Reis (Author), Leandra da Silva Paes (Author), Ana Carolina de Azevedo Carvalho (Author), Nádia Maria S. Marques (Author), Marcelo Guimarães (Author), Marcelo Aranha Gardel (Author), Sonia Oliveira Souza (Author), Simone Marques Fernandes (Author), Fernanda Oliveira Laranjeira (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2003-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the present work was to develop a qualitative chronopathological study concerning abnormalities in myocardium, due to nitric oxide (NO) blockage. We used 60 Wistar normotensive young male rats from several breeds. Groups of rats were submitted to L-Name (L) via oral administration dissolv...