Results of a phase I/IIa trial of SV-BR-1-GM inoculation with low-dose cyclophosphamide and interferon alpha (Bria-IMT) in metastatic breast cancer

• Main Authors: Charles L. Wiseman (Author), Jarrod P. Holmes (Author), Carmen Calfa (Author), Shaker R. Dakhil (Author), Saveri Bhattacharya (Author), George E. Peoples (Author), Markus D. Lacher (Author), Miguel Lopez-Lago (Author), Alex Kharazi (Author), Giuseppe Del Priore (Author), Mingjin Chang (Author), Daniel L. Adams (Author), William V. Williams (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This Phase I/IIa open-label, single-arm clinical trial addressing advanced, refractory, metastatic breast cancer was conducted at six medical centers in the United States. We repeated inoculations with irradiated SV-BR-1-GM, a breast cancer cell line with antigen-presenting activity engineered to re...