GlycoVHH: optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery

• Үндсэн зохиолчид: Loes van Schie (Зохиогч), Wander Van Breedam (Зохиогч), Charlotte Roels (Зохиогч), Bert Schepens (Зохиогч), Martin Frank (Зохиогч), Ahmad Reza Mehdipour (Зохиогч), Bram Laukens (Зохиогч), Wim Nerinckx (Зохиогч), Francis Santens (Зохиогч), Simon Devos (Зохиогч), Iebe Rossey (Зохиогч), Karel Thooft (Зохиогч), Sandrine Vanmarcke (Зохиогч), Annelies Van Hecke (Зохиогч), Xavier Saelens (Зохиогч), Nico Callewaert (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

ABSTRACTAs small and stable high-affinity antigen binders, VHHs boast attractive characteristics both for therapeutic use in various disease indications, and as versatile reagents in research and diagnostics. To further increase the versatility of VHHs, we explored the VHH scaffold in a structure-gu...