Serotonin as a biomarker of toxin-induced Parkinsonism

• Main Authors: Anna Marie Buchanan (Author), Sergio Mena (Author), Iman Choukari (Author), Aditya Vasa (Author), Jesseca N. Crawford (Author), Jim Fadel (Author), Nick Maxwell (Author), Lawrence Reagan (Author), Allie Cruikshank (Author), Janet Best (Author), H. Fred Nijhout (Author), Michael Reed (Author), Parastoo Hashemi (Author)
• Format: Book
• Published: BMC, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Loss of dopaminergic neurons underlies the motor symptoms of Parkinson's disease (PD). However stereotypical PD symptoms only manifest after approximately 80% of dopamine neurons have died making dopamine-related motor phenotypes unreliable markers of the earlier stages of t...