The Potential Effects of Quercetin-Loaded Nanoliposomes on Amoxicillin/Clavulanate-Induced Hepatic Damage: Targeting the SIRT1/Nrf2/NF-κB Signaling Pathway and Microbiota Modulation

• Main Authors: Mahran Mohamed Abd El-Emam (Author), Mahmoud Mostafa (Author), Amina A. Farag (Author), Heba S. Youssef (Author), Azza S. El-Demerdash (Author), Heba Bayoumi (Author), Mohammed A. Gebba (Author), Sawsan M. El-Halawani (Author), Abdulrahman M. Saleh (Author), Amira M. Badr (Author), Shorouk El Sayed (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amoxicillin/clavulanate (Co-Amox), a commonly used antibiotic for the treatment of bacterial infections, has been associated with drug-induced liver damage. Quercetin (QR), a naturally occurring flavonoid with pleiotropic biological activities, has poor water solubility and low bioavailability. The...