Therapeutic effect and mechanism of combination therapy with ursolic acid and insulin on diabetic nephropathy in a type I diabetic rat model

• Main Authors: Yang Liu (Author), Jin-Yan Zheng (Author), Zhi-Tao Wei (Author), Shu-Kun Liu (Author), Ji-Lei Sun (Author), Yin-Hui Mao (Author), Yong-De Xu (Author), Yong Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This work aims to investigate the therapeutic effect of ursolic acid (UA) plus insulin (In) on diabetic nephropathy (DN) in streptozotocin (STZ)-induced T1DM rats. The experimental groups and operational details are as follows: A total of thirty-two SD rats were divided into four groups: the DN mode...