MnTnHex-2-PyP⁵⁺ Displays Anticancer Properties and Enhances Cisplatin Effects in Non-Small Cell Lung Cancer Cells

• Main Authors: Rita B. Soares (Author), Rita Manguinhas (Author), João G. Costa (Author), Nuno Saraiva (Author), Nuno Gil (Author), Rafael Rosell (Author), Sérgio P. Camões (Author), Ines Batinic-Haberle (Author), Ivan Spasojevic (Author), Matilde Castro (Author), Joana P. Miranda (Author), Filipa Amaro (Author), Joana Pinto (Author), Ana S. Fernandes (Author), Paula Guedes de Pinho (Author), Nuno G. Oliveira (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The manganese(III) porphyrin MnTnHex-2-PyP⁵⁺ (MnTnHex) is a potent superoxide dismutase mimic and modulator of redox-based transcriptional activity that has been studied in the context of different human disease models, including cancer. Nevertheless, for lung cancer, hardly a...