Bioanalytical LC-QTOF/MS Method for a <i>N</i>-phenylpiperazine Derivate (LQFM05): An Anxiolytic- and Antidepressant-like Prototype Drug Applied to Pharmacokinetic and Biodistribution Studies

Bioanalytical LC-QTOF/MS Method for a <i>N</i>-phenylpiperazine Derivate (LQFM05): An Anxiolytic- and Antidepressant-like Prototype Drug Applied to Pharmacokinetic and Biodistribution Studies

The LQFM05 is a prototype drug designed for treatment of psychiatric disorders, such as schizophrenia, exhibiting anxiolytic- and antidepressant-like (12 or 24 µmol/kg) effects in classical behavioral tests. In order to evaluate its pharmacokinetic properties, a liquid chromatography method coupled...

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Main Authors: Ana Cláudia M. Ramos (Author), Kênnia R. Rezende (Author), Carolina M. Teixeira (Author), Aline R. Fernandes (Author), Heloa Santos (Author), Rúbia Darc Machado (Author), Ricardo Menegatti (Author), Boniek G. Vaz (Author), Andréa R. Chaves (Author)
Format: Book
Published: MDPI AG, 2023-06-01T00:00:00Z.
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3rd Floor Main Library

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