Effect of Extracellular Matrix Stiffness on Candesartan Efficacy in Anti-Fibrosis and Antioxidation

• প্রধান লেখক: Tong Zhu (লেখক), Jingjing Song (লেখক), Bin Gao (লেখক), Junjie Zhang (লেখক), Yabei Li (লেখক), Zhaoyang Ye (লেখক), Yuxiang Zhao (লেখক), Xiaogang Guo (লেখক), Feng Xu (লেখক), Fei Li (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2023-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Myocardial fibrosis progression and imbalanced redox state are closely associated with increased extracellular matrix (ECM) stiffness. Candesartan (CAN), an angiotensin II (Ang II) receptor inhibitor, has shown promising anti-fibrosis and antioxidant efficacy in previous cardiovascular disease studi...