Folate-targeted nanostructured chitosan/chondroitin sulfate complex carriers for enhanced delivery of bortezomib to colorectal cancer cells

• Main Authors: Zar Chi Soe (Author), Bijay Kumar Poudel (Author), Hanh Thuy Nguyen (Author), Raj Kumar Thapa (Author), Wenquan Ou (Author), Milan Gautam (Author), Kishwor Poudel (Author), Sung Giu Jin (Author), Jee-Heon Jeong (Author), Sae Kwang Ku (Author), Han-Gon Choi (Author), Chul Soon Yong (Author), Jong Oh Kim (Author)
• Format: Book
• Published: Elsevier, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Folate-targeting self-assembled nanoparticles (NPs) using biocompatible and biodegradable natural polymers chitosan (Cs) and chondroitin sulfate (Chs) were developed to address the major challenge in cancer treatment, the selective delivery of nanoparticles to the target site. In this study, we succ...