Restoration of miR-193a-5p and miR-146 a-5p Expression Induces G1 Arrest in Colorectal Cancer through Targeting of MDM2/p53

• Main Authors: Saeed Noorolyai (Author), Elham Baghbani (Author), Leili Aghebati Maleki (Author), Amir Baghbanzadeh Kojabad (Author), Dariush Shanehbansdi (Author), Vahid Khaze Shahgoli (Author), Ahad Mokhtarzadeh (Author), Behzad Baradaran (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Colorectal cancer (CRC) remains a universal and lethal cancer owing to metastatic and relapsing disease. Currently, the role of microRNAs has been checked in tumorigeneses. Numerous studies have revealed that between the tumor suppressor miRNAs, the reduced expression of miR-146a-5p and -19...