Effects of 4,4'-Diisothiocyanato-stilbene-2,2'-disulfonic Acid (DIDS) and Chlorpromazine on NO3- Transport via Anion Exchanger in Erythrocytes: Inertness of DIDS in Whole Blood

• Main Authors: Kaname Kubota (Author), Takaharu Ishibashi (Author), Taku Matsubara (Author), Tomoyuki Hori (Author), Kazuyuki Ozaki (Author), Masaru Yamazoe (Author), Junko Yoshida (Author), Matomo Nishio (Author), Yoshifusa Aizawa (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT: We examined the effects of chlorpromazine on NO3- transport between erythrocytes (RBCs) and extracellular fluid. Chlorpromazine (10 μg/ml) did not influence NO3- movement in both whole blood and RBC suspension. Though an anion exchanger (AE1) inhibitor DIDS (4,4'-diisothiocyanato-stil...