Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease

• Main Authors: Chris E. Shannon (Author), Mukundan Ragavan (Author), Juan Pablo Palavicini (Author), Marcel Fourcaudot (Author), Terry M Bakewell (Author), Ivan A. Valdez (Author), Iriscilla Ayala (Author), Eunsook S. Jin (Author), Muniswamy Madesh (Author), Xianlin Han (Author), Matthew E. Merritt (Author), Luke Norton (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Insulin resistance and altered hepatic mitochondrial function are central features of type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD), but the etiological role of these processes in disease progression remains unclear. Here we investigated the molecular links between i...