Mesoporous Silica as an Alternative Vehicle to Overcome Solubility Limitations

• Main Authors: Tim Becker (Author), Jan Heitkötter (Author), Anna K. Krome (Author), Andrea Schiefer (Author), Kenneth Pfarr (Author), Alexandra Ehrens (Author), Miriam Grosse (Author), Birthe Sandargo (Author), Ingo Stammberger (Author), Marc Stadler (Author), Marc P. Hübner (Author), Stefan Kehraus (Author), Achim Hoerauf (Author), Karl G. Wagner (Author)
• Format: Book
• Published: MDPI AG, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Toxicological studies are a part of the drug development process and the preclinical stages, for which suitable vehicles ensuring easy and safe administration are crucial. However, poor aqueous solubility of drugs complicates vehicle screening for oral administration since non-aqueous solvents are o...