Polymeric ethosomal gel loaded with nimodipine: Optimisation, pharmacokinetic and histopathological analysis

• Main Authors: Jamal Moideen Muthu Mohamed (Author), Barkat A Khan (Author), Vijaya Rajendran (Author), Mohamed El-Sherbiny (Author), Gamal Othman (Author), Abdulrahman Bashir Ahmed Hussamuldin (Author), Rasha Hamed Al-Serwi (Author)
• Format: Book
• Published: Elsevier, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study was performed with the main objective of formulating and evaluating the potential of ethosomesl gel (Etho gel) to deliver nimodipine (NiM) for cardiovascular disease, a potent water insoluble anti-hypertensive drug via skin to reach the deeper layers of skin. The Box-Behnken design (BBD)...