Screening and evaluation of metabolites binding PRAS40 from Erxian decoction used to treat spinal cord injury
Objective: The PRAS40 is an essential inhibitory subunit of the mTORC1 complex, which regulates autophagy. It has been suggested that Erxian Decoction (EXD) could treat spinal cord injury (SCI) via the autophagy pathway. However, the mechanism of whether EXD acts through PRAS40 remains unclear.Metho...
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Frontiers Media S.A.,
2024-01-01T00:00:00Z.
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