Low aerobic capacity in McArdle disease: A role for mitochondrial network impairment?

• Główni autorzy: M. Villarreal-Salazar (Autor), A. Santalla (Autor), A. Real-Martínez (Autor), G. Nogales-Gadea (Autor), P.L. Valenzuela (Autor), C. Fiuza-Luces (Autor), A.L. Andreu (Autor), J.C. Rodríguez-Aguilera (Autor), M.A. Martín (Autor), J. Arenas (Autor), J. Vissing (Autor), A. Lucia (Autor), T.O. Krag (Autor), T. Pinós (Autor)
• Format: Książka
• Wydane: Elsevier, 2022-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background: McArdle disease is caused by myophosphorylase deficiency and results in complete inability for muscle glycogen breakdown. A hallmark of this condition is muscle oxidation impairment (e.g., low peak oxygen uptake (VO2peak)), a phenomenon traditionally attributed to reduced glycolytic flux...