Ursolic Acid Inhibits Collective Cell Migration and Promotes JNK-Dependent Lysosomal Associated Cell Death in Glioblastoma Multiforme Cells

• Главные авторы: Gillian E. Conway (Автор), Deimante Zizyte (Автор), Julie Rose Mae Mondala (Автор), Zhonglei He (Автор), Lorna Lynam (Автор), Mathilde Lecourt (Автор), Carlos Barcia (Автор), Orla Howe (Автор), James F. Curtin (Автор)
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• Опубликовано: MDPI AG, 2021-01-01T00:00:00Z.
• Предметы: article
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Ursolic acid (UA) is a bioactive compound which has demonstrated therapeutic efficacy in a variety of cancer cell lines. UA activates various signalling pathways in Glioblastoma multiforme (GBM) and offers a promising starting point in drug discovery; however, understanding the relationship between...