Functional Characterisation of Human CYP2C9 Allelic Variants in COS-7 cells

• Váldodahkkit: Huihui eDu (Dahkki), Zhiyun eWei (Dahkki), Yucai eYan (Dahkki), Yuyu eXiong (Dahkki), Xiaoqing eZhang (Dahkki), Lu eShen (Dahkki), Yunfeng eRuan (Dahkki), Xi eWu (Dahkki), Qingqing eXu (Dahkki), Lin eHe (Dahkki), Shengying eQin (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2016-04-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Variability in activity of CYP2C9, which is involved in the metabolism of approximately 15% of current therapeutic drugs, is an important contributor to interindividual differences in drug response. To evaluate the functional alternations of CYP2C9*2, CYP2C9*3, CYP2C9*8, CYP2C9*11 and CYP2C9*31, ide...