Anabolic effects and inhibition of interleukin 6 production induced by neridronate on human osteoblasts

• Main Authors: S. Niccolini (Author), F. Chellini (Author), F. Baldi (Author), P. Ferrata (Author), D. Gambera (Author), C. Capperucci (Author), B. Frediani (Author), A. Spreafico (Author), L. Bocchi (Author), R. Marcolongo (Author)
• Format: Book
• Published: PAGEPress Publications, 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bisphosphonates (BPs) are pharmacological compounds widely used in the treatment of a variety of bone-related diseases, particularly where the bone-turnover is skewed in favour of osteolysis. The mechanisms by which BPs reduce bone-resorption directly acting on osteoclasts (OCs) are now largely clar...