Susceptibility to Ventricular Arrhythmias Resulting from Mutations in FKBP1B, PXDNL, and SCN9A Evaluated in hiPSC Cardiomyocytes

• 主要な著者: Hector Barajas-Martinez (著者), Maya Smith (著者), Dan Hu (著者), Robert J. Goodrow (著者), Colleen Puleo (著者), Can Hasdemir (著者), Charles Antzelevitch (著者), Ryan Pfeiffer (著者), Jacqueline A. Treat (著者), Jonathan M. Cordeiro (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2020-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background. We report an inherited cardiac arrhythmia syndrome consisting of Brugada and Early Repolarization Syndrome associated with variants in SCN9A, PXDNL, and FKBP1B. The proband inherited the 3 mutations and exhibited palpitations and arrhythmia-mediated syncope, whereas the parents and siste...