Ligustrazine alleviates pulmonary arterial hypertension in rats by promoting the formation of myocardin transcription complex in the nucleus of pulmonary artery smooth muscle cells

• Main Authors: Xichao Yu (Author), Mingjie Wu (Author), Qinhai Meng (Author), Weijie Zhu (Author), Chenyan Zhang (Author), Bowen Liu (Author), Yuewen Qi (Author), Shuqun Gu (Author), Xinyu Wang (Author), Jingli Wen (Author), Yu Li (Author), Xu Qi (Author)
• Format: Book
• Published: Wiley, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Pulmonary arterial hypertension (PAH) is a pathophysiological state of abnormally elevated pulmonary arterial pressure caused by drugs, inflammation, toxins, viruses, hypoxia, and other risk factors. We studied the therapeutic effect and target of tetramethylpyrazine (tetramethylpyrazine [T...