Improved up-and-down procedure for acute toxicity measurement with reliable LD50 verified by typical toxic alkaloids and modified Karber method

Abstract Background Up-and-down procedure (UDP) was recommended to replace traditional acute toxicity methods. However, it was limited due to the long experimental period (20-42 days). To improve UDP, an improved UDP method (iUDP) was developed by shortening observation time between sequence dosages...

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Main Authors: Yan-Yu Zhang (Author), Yu-Feng Huang (Author), Jie Liang (Author), Hua Zhou (Author)
Format: Book
Published: BMC, 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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