Muscarinic cholinoceptor-mediated activation of JNK negatively regulates intestinal secretion in mice

• Main Authors: Md Rafiqul Islam Khan (Author), Md Tariqul Islam (Author), Takashi Yazawa (Author), Hisayoshi Hayashi (Author), Yuichi Suzuki (Author), Junsuke Uwada (Author), Abu Syed Md Anisuzzaman (Author), Takanobu Taniguchi (Author)
• Format: Book
• Published: Elsevier, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Regulation of intestinal secretion is important for body fluid homeostasis. We investigated the role of three MAP kinases (MAPKs) as negative regulators in muscarinic cholinoceptor (mAChR)-mediated intestinal secretion in mice. Electrophysiological analyses revealed that mAChR stimulation enhanced i...