Valproic Acid Induces Endothelial-to-Mesenchymal Transition-Like Phenotypic Switching

Valproic Acid Induces Endothelial-to-Mesenchymal Transition-Like Phenotypic Switching

Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, is a widely used anticonvulsant drug that is currently undergoing clinical evaluation for anticancer therapy due to its anti-angiogenic potential. Endothelial cells (ECs) can transition into mesenchymal cells and this form of EC plasticity...

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Main Authors: Shamini Murugavel (Author), Antoinette Bugyei-Twum (Author), Pratiek N. Matkar (Author), Husain Al-Mubarak (Author), Hao H. Chen (Author), Mohamed Adam (Author), Shubha Jain (Author), Tanya Narang (Author), Rawand M. Abdin (Author), Mohammad Qadura (Author), Kim A. Connelly (Author), Howard Leong-Poi (Author), Krishna K. Singh (Author)
Format: Book
Published: Frontiers Media S.A., 2018-07-01T00:00:00Z.
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