TIMP1 regulates ferroptosis in osteoblasts by inhibiting TFRC ubiquitination: an in vitro and in vivo study

• Main Authors: Bo Peng (Author), Zhiwei Feng (Author), Ao Yang (Author), Jinmin Liu (Author), Jinwen He (Author), Lihu Xu (Author), Cong Tian (Author), Xiaoyun Sheng (Author), Yaobin Wang (Author), Rongjin Chen (Author), Xingwen Wang (Author), Xiaojun Ren (Author), Bin Geng (Author), Yayi Xia (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background In clinical practice, alterations in the internal environment of type 2 diabetes can significantly affect bone quality. While the increased risk of fractures among diabetic patients is well-established, the precise mechanisms by which hyperglycemia influences bone quality remain...