Growth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa cells of patients with polycystic ovary syndrome

• Үндсэн зохиолчид: Yan Gong (Зохиогч), Shan Luo (Зохиогч), Ping Fan (Зохиогч), Huili Zhu (Зохиогч), Yujing Li (Зохиогч), Wei Huang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: BMC, 2020-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Background It is reported that growth hormone (GH) can alleviate oxidative stress (OS) induced apoptosis in some types of cells by activating the PI3K/Akt signaling pathway. This study investigated the role and underlying mechanism of GH in OS and apoptosis in granulosa cells (GCs) of patie...