New Aspects for the Treatment of Cardiac Diseases Based on the Diversity of Functional Controls on Cardiac Muscles: Diversity in the Excitation-Contraction Mechanisms of the Heart

• Main Authors: Hikaru Tanaka (Author), Iyuki Namekata (Author), Hideaki Nouchi (Author), Koki Shigenobu (Author), Toru Kawanishi (Author), Akira Takahara (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The waveform of the myocardial action potential (AP) triggering contraction differs among the species, developmental stage, and pathological state. The species difference in heart rate, which inversely correlates with body size, originates in the ion-channel mechanisms responsible for diastolic depo...