Use of polymer combinations in the preparation of solid dispersions of a thermally unstable drug by hot-melt extrusion

The objective of the study was to prepare solid dispersions containing a thermally unstable drug by hot-melt extrusion (HME). Carbamazepine (CBZ) was selected as model drug and combinations of Kollidon VA64 (VA64), Soluplus (SOL) and Eudragit EPO (EPO) were utilized as carriers. Preformulation was c...

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Bibliographic Details
Main Authors: Jia Liu (Author), Feng Cao (Author), Can Zhang (Author), Qineng Ping (Author)
Format: Book
Published: Elsevier, 2013-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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