Use of polymer combinations in the preparation of solid dispersions of a thermally unstable drug by hot-melt extrusion
The objective of the study was to prepare solid dispersions containing a thermally unstable drug by hot-melt extrusion (HME). Carbamazepine (CBZ) was selected as model drug and combinations of Kollidon VA64 (VA64), Soluplus (SOL) and Eudragit EPO (EPO) were utilized as carriers. Preformulation was c...
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Format: | Book |
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Elsevier,
2013-07-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |