Characterization and Activation of NLRP3 Inflammasomes in the Renal Medulla in Mice

• Main Authors: Min Xia (Author), Justine M. Abais (Author), Saisudha Koka (Author), Nan Meng (Author), Todd W. Gehr (Author), Krishna M. Boini (Author), Pin-Lan Li (Author)
• Format: Book
• Published: Karger Publishers, 2016-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Recent studies have indicated that local inflammatory mediators are importantly involved in the regulation of renal function. However, it remains unknown how such local inflammation is triggered intracellularly in the kidney. The present study was designed to characterize the inflam...