ATF1/miR-214-5p/ITGA7 axis promotes osteoclastogenesis to alter OVX-induced bone absorption

• Main Authors: Lu-Lin Liu (Author), Yao-Sheng Xiao (Author), Wei-Min Huang (Author), Sheng Liu (Author), Li-Xing Huang (Author), Jing-Hua Zhong (Author), Peng Jia (Author), Wu-Yang Liu (Author)
• Format: Book
• Published: BMC, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The dynamic balance of osteoblast and osteoclast is critical for bone homeostasis and overactive osteoclastic function may lead to osteoporosis. Activating transcription factor 1 (ATF1) is involved in osteoclastogenesis. However, the detailed mechanisms remain to be explored. Met...