Carvedilol increases seizure resistance in a mouse model of SCN8A-derived epilepsy

• Những tác giả chính: Jennifer C. Wong (Tác giả), Andrew Escayg (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Patients with mutations that alter the function of the sodium channel SCN8A present with a range of clinical features, including mild to severe seizures, developmental delay, intellectual disability, autism, feeding dysfunction, motor impairment, and hypotonia. In an effort to identify compounds tha...