The frequent <it>BRCA1 </it>mutation 1135insA has multiple origins: a haplotype study in different populations

• Main Authors: Møller Pål (Author), Gille Johan JP (Author), Hogervorst Frans (Author), Galvez Maria (Author), Hamel Nancy (Author), Rudkin Teresa M (Author), Apold Jaran (Author), Foulkes William D (Author)
• Format: Book
• Published: BMC, 2006-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Analysis of the chromosomal background upon which a mutation occurs can be used to reconstruct the origins of specific disease-causing mutations. The relatively common <it>BRCA1 </it>mutation, 1135insA, has been previousl...