Formulation of Stable and Homogeneous Cell-Penetrating Peptide NF55 Nanoparticles for Efficient Gene Delivery In Vivo

• Main Authors: Krista Freimann (Author), Piret Arukuusk (Author), Kaido Kurrikoff (Author), Ly Pärnaste (Author), Raivo Raid (Author), Andres Piirsoo (Author), Margus Pooga (Author), Ülo Langel (Author)
• Format: Book
• Published: Elsevier, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although advances in genomics and experimental gene therapy have opened new possibilities for treating otherwise incurable diseases, the transduction of nucleic acids into the cells and delivery in vivo remain challenging. The high molecular weight and anionic nature of nucleic acids require their p...