NEDD4L in human tumors: regulatory mechanisms and dual effects on anti-tumor and pro-tumor

• Hoofdauteurs: Meng Zhang (Auteur), Zhenyong Zhang (Auteur), Xin Tian (Auteur), Enchong Zhang (Auteur), Yichun Wang (Auteur), Jun Tang (Auteur), Jianzhu Zhao (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Tumorigenesis and tumor development are closely related to the abnormal regulation of ubiquitination. Neural precursor cell expressed developmentally downregulated 4-like (NEDD4L), an E3 ubiquitin ligase critical to the ubiquitination process, plays key roles in the regulation of cancer stem cells,...