Immunostimulatory activity and structure-activity relationship of epimedin B from Epimedium brevicornu Maxim.

• Main Authors: Yuan Gao (Author), Wei Shi (Author), Can Tu (Author), Peng Li (Author), Guanyu Zhao (Author), Xiaohe Xiao (Author), Jiabo Wang (Author), Zhaofang Bai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epimedii Folium (EF, Epimedium brevicornu Maxim.), a traditional botanical drug, is famous for treating bone fractures, joint diseases, and several chronic illnesses. However, some studies indicated that EF could induce idiosyncratic drug-induced liver injury (IDILI) in the clinic. The NLRP3 inflamm...