Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes

• Główni autorzy: Angela Maria Cozzolino (Autor), Valeria Noce (Autor), Cecilia Battistelli (Autor), Alessandra Marchetti (Autor), Germana Grassi (Autor), Carla Cicchini (Autor), Marco Tripodi (Autor), Laura Amicone (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2016-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

In many cell types, several cellular processes, such as differentiation of stem/precursor cells, maintenance of differentiated phenotype, motility, adhesion, growth, and survival, strictly depend on the stiffness of extracellular matrix that, in vivo, characterizes their correspondent organ and tiss...