Signal Detection of Potentially Drug-Induced Liver Injury in Children Using Electronic Health Records

• Main Authors: Yuncui Yu (Author), Xiaolu Nie (Author), Ziyang Song (Author), Yuefeng Xie (Author), Xuan Zhang (Author), Zhaoyang Du (Author), Ran Wei (Author), Duanfang Fan (Author), Yiwei Liu (Author), Qiuye Zhao (Author), Xiaoxia Peng (Author), Lulu Jia (Author), Xiaoling Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: This study proposes a quantitative 2-stage procedure to detect potential drug-induced liver injury (DILI) signals in pediatric inpatients using an data warehouse of electronic health records (EHRs).Methods: Eight years of medical data from a constructed database were used. A two-stage pr...