Association between tenofovir plasma trough concentrations in the early stage of administration and discontinuation of up to five years tenofovir disoproxil fumarate due to renal function-related adverse events in Japanese HIV-1 infected patients

• Main Authors: Hiroki Yagura (Author), Dai Watanabe (Author), Takao Nakauchi (Author), Hiroyuki Kushida (Author), Kazuyuki Hirota (Author), Yasuharu Nishida (Author), Munehiro Yoshino (Author), Tomoko Uehira (Author), Takuma Shirasaka (Author)
• Format: Book
• Published: BMC, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The relationship between plasma tenofovir (TFV) concentration at the beginning of tenofovir disoproxil fumarate (TDF) administration and the development of renal dysfunction during long-term administration of TDF has not been demonstrated yet. The objective of the present study w...