Activation of Nrf2/Keap1 pathway by oral Dimethylfumarate administration alleviates oxidative stress and age-associated infertility might be delayed in the mouse ovary

• मुख्य लेखकों: Nana Akino (लेखक), Osamu Wada-Hiraike (लेखक), Wataru Isono (लेखक), Hiromi Terao (लेखक), Harunori Honjo (लेखक), Yuichiro Miyamoto (लेखक), Michihiro Tanikawa (लेखक), Kenbun Sone (लेखक), Mana Hirano (लेखक), Miyuki Harada (लेखक), Tetsuya Hirata (लेखक), Yasushi Hirota (लेखक), Kaori Koga (लेखक), Katsutoshi Oda (लेखक), Tomoyuki Fujii (लेखक), Yutaka Osuga (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2019-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Age-associated infertility is a problem worldwide, and management of oxidative stress is known to be essential. Nuclear factor-E2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1)-antioxidant response element (ARE) signaling pathway works as an essential defense...